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Benzodiazepines and anxiety disorders: a risky bet
According to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), anxiety disorders are a group of mental disorders characterised by significant and ongoing feelings of worry and fear. They include agoraphobia, panic disorder, social phobia, and generalised anxiety disorder (American Psychiatric Association, 2013). They constitute the most prevalent subgroup of mental disorders, with up … Read More
Challenges of memory-sparing medication for Alzheimer’s disease
Alzheimer’s disease is a chronic neurodegenerative brain disorder typically occurring in middle or late life which is characterised by progressive dementia, with three main pathological symptoms: degeneration of acetylcholine cells, accumulation of extracellular plaque, and intracellular neurofibrillary tangles (McKhann et al., 1984). Its global prevalence in people aged 60+ was estimated to be 3.9%, with … Read More
How effective are early interventions in psychosis services?
According to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), psychosis is a common symptom in a spectrum of psychotic disorders including schizophrenia and delusional disorder (American Psychiatric Association, 2013; Arciniegas, 2015). Classified as a clinical syndrome rather than a nosological entity (or distinct disease), psychosis is characterised by clinical features such as … Read More
Ownership and Intellectual Property Rights
The content on this website, including, but not limited to, articles, graphics, designs and frameworks, is the property of Ness Labs LTD and is protected by copyright and, where applicable, other intellectual property laws. The content is the original work of Anne-Laure Le Cunff and the Ness Labs team unless otherwise stated. Permitted Use Ness … Read More
A quick overview of the polymerase chain reaction
The polymerase chain reaction (PCR) is a laboratory method that allows researchers to produce a significant amount of specific DNA using trace amounts of source DNA, which can be obtained from a variety of organisms and tissues (Garibyan & Avashia, 2013). When discovered in the 1980s, the technique – which can produce billions of copies … Read More
Teeny Breaks
Teeny Breaks is a free Chrome extension offering science-based tips for mindful breaks. Winner of the Product Hunt Maker Festival in the “Brain” category, winner of the 24-Hour Startup Challenge, 5-star rating on the Chrome store, 600+ active users. When you open a new tab, Teeny Breaks displays a mindfulness tip so you can make … Read More
Measuring brain function: how do fMRI scanners work?
In 1977, Dr. Raymond Damadian performed the first magnetic resonance imaging (MRI) scan on a live human patient (Edelman, 2014). MRI is a non-invasive medical imaging technique producing detailed pictures of anatomical structures and physiological processes inside the body (McRobbie et al., 2017). MRI scans are considered safer than CT scans and PET scans as … Read More
My pivotal 2018: from startup founder to indie maker
This year felt longer than usual. So much has happened it’s hard to believe it was only 365 days. It’s been a long time I haven’t written this type of self-reflection article, but 2018 has been such a pivotal year that I wanted to take a moment to look back. Up to 2017, my career … Read More
Schizophrenia and dendritic spines
Pyramidal neurons are the primary type of cells in the cerebral cortex; they are made of a cell body called soma, a single axon, an apical dendrite, multiple basal dendrites, and dendritic spines (Megias et al., 2001). Dendritic spines are small neuronal protrusions rising from a neuron’s dendrites; they typically receive excitatory input from one … Read More