Plus Minus Next journaling

At this point, most people know about the benefits of journaling. Read any self-development blog and you will stumble on at least one article telling you why keeping a journal will change your life. The problem? Most people can’t build the habit. We know we should keep a journal. But we don’t know how to … Read More

Ten keys to happier living

A few weeks ago, I took a training to become a certified Mental Health First Aider. It’s an amazing evidence-based training which has been designed in partnership with the NHS and is accredited by the Royal Society for Public Health. Here is the link if you’d like to take it in England, but they offer … Read More

Impostor syndrome: the fear of being exposed as a fraud

“I am not a writer. I’ve been fooling myself and other people.” John Steinbeck, very talented and successful author who won the 1962 Nobel Prize in Literature. Yesterday, I launched my newsletter on Product Hunt. The launch went incredibly well, with 1,300 new subscribers joining the list, lots of kind comments, and a second spot … Read More

Taking note of nature

I just spent the weekend in Champagne, France, in an old country house, with good food and good friends. Despite the rain, we spent most of our time outside observing the flowers, trees, and the insects and animals roaming the land. This was the first time in a long time where I didn’t touch my … Read More

How stress and anxiety impact your ability to focus

Negative emotions such as stress and anxiety can have an effect on cognitive processes, with many studies showing that inducing negative mood states in individuals leads to a reduction in executive functions (Grant et al, 2001; Hammar & Ardal, 2009). This reduction may be caused by a depletion in limited attention resources in individuals experiencing … Read More

Personalised medicine and mental health

Personalised medicine is a medical model that tailors treatment to individuals based on genetic, epigenomic, and clinical information (Mathur & Sutton, 2017). Also called precision medicine (Boguski et al., 2009), P4 medicine (Flores et al., 2013) or stratified medicine (Trusheim et al., 2007), it is anticipated to have a major effect on both the development … Read More

Mental disorders in high versus low income countries

Psychiatric epidemiology studies the distribution and causal mechanisms of mental disorders in the population (McQuistion, 2008). It is a branch of epidemiology with its own set of challenges, including difficult assessment of caseness, high comorbidity, complex measurement of risk-factors such as stress or lack of social support, costly diagnostics, and information bias (Burger & Neeleman, … Read More

How effective are early interventions in psychosis services?

According to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), psychosis is a common symptom in a spectrum of psychotic disorders including schizophrenia and delusional disorder (American Psychiatric Association, 2013; Arciniegas, 2015). Classified as a clinical syndrome rather than a nosological entity (or distinct disease), psychosis is characterised by clinical features such as … Read More

Schizophrenia and dendritic spines

Pyramidal neurons are the primary type of cells in the cerebral cortex; they are made of a cell body called soma, a single axon, an apical dendrite, multiple basal dendrites, and dendritic spines (Megias et al., 2001). Dendritic spines are small neuronal protrusions rising from a neuron’s dendrites; they typically receive excitatory input from one … Read More